stemCARE

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stemCARE

stemCARE offers the creation, bioproduction and cryopreservation of cellular models for genetic diseases based on human pluripotent stem cells and their progenies. It supports users in the study of molecular and functional disorders associated with these diseases thanks to high-throughput sequencing technologies and advanced analytical platforms.
In addition, stemCARE assists in the search for potential pharmacological compounds by screening repositionable molecules or new chemical entities in partnership with collection owners.

The platform also offers training in cell culture techniques, quality control and autonomous use of equipment.

Labels

 

GenoTher (2025) GIS IBISA (2024) Génopole (2022)
genother    
  
logo de IBISA   
genopole    

Contact : abenchoua[AT]istem.fr


The stemCARE platform is distinguished by its six integrated technology platforms:

Team members

BioProduction


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Cell Biology

 

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Genome editing

 

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High-throughput sequencing

 

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High-throughput screening

 

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Cell Imaging

 

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Publications

High-throughput screening identifies bazedoxifene as a potential therapeutic for dysferlin-deficient limb girdle muscular dystrophy.

01 July 2025

Bruge Celine,

Bourg Nathalie,

Pellier Emilie,

Tournois Johana,

Polentes Jerome,

Benabides Manon,

Grossi Noella,

Bigot Anne,

Brureau Anthony,

Richard Isabelle,

Nissan Xavier,

British journal of pharmacology

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Inhibition of poly(ADP-Ribosyl)ation reduced vascular smooth muscle cells loss and improves aortic disease in a mouse model of human accelerated aging syndrome.

02 October 2024

Cardoso Déborah,

Guilbert Solenn,

Guigue Philippe,

Carabalona Aurélie,

Harhouri Karim,

Peccate Cécile,

Tournois Johana,

Guesmia Zoheir,

Ferreira Lino,

Bartoli Catherine,

Levy Nicolas,

Colleaux Laurence,

Nissan Xavier,

Muchir Antoine,

Cell death & disease

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Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models.

10 June 2024

Thibaudeau Amandine,

Schmitt Karen,

François Louise,

Chatrousse Laure,

Hoffmann David,

Cousin Loic,

Weiss Amélie,

Vuidel Aurore,

Jacob Christina B,

Sommer Peter,

Benchoua Alexandra,

Wilbertz Johannes H,

Translational psychiatry

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